Outcome Parameters List
Pharmacokinetics
- CSF/Serum Ratio
- Drug Concentration-Blood
- Drug Concentration-Brain
- Drug Concentration-CSF
- Drug Concentration-Organs
- Drug Concentration-Plasma
- Drug Concentration-Serum
- Drug Uptake-Brain Cells
- Elimination Rate Constant (Ke)
- Free Drug Concentration-Brain
- Free Drug Concentration-CSF
- Free Drug Concentration-Plasma
- Free Fraction-Plasma
- Gene Delivery to Brain
- Kinetic Solubility
- Liposome Concentration-Blood
- Liposome Concentration-Brain
- Liposome Concentration-Organs
- LogP
- Mean Residence Time (MRT)
- Metabolite Concentration-Brain
- Metabolite Concentration-Plasma
- Michaelis-Menten Enzyme Metabolism Constant (Km)
- Minimum Effective Dose (MED)
- Oral Bioavailability (F%)
- PK/PD Modeling
- Plasma Protein Binding
- Plasma t1/2
- Recombinant Protein Concentration-Blood
- Recombinant Protein Concentration-Liver
- Residual Plasma Volume
- Serum t1/2
- t1/2 (Elimination Half-Life)
- Tmax
- Variance of Residence Time (VRT)
- Volume of Distribution (V)
- Volume of Distribution at Steady State (Vss)
- Volume of Distribution During Terminal Phase (Vz)
Pharmacology
- Binding Affinity
- Cerep Profile
- Competitive Inhibition
- Potency
- Receptor Agonism
- Receptor Antagonism
- Receptor Inverse Agonism
- Target Screen
- Target Selectivity
Physiology
- Audiogenic Seizures
- Blood Gas Measurement
- Blood Pressure
- Brown Adipose Tissue (BAT) Thermogenesis
- Carotid Blood Flow
- Cerebral Blood Flow (CBF)
- Cerebrovascular Reactivity
- Coagulation Parameters
- Colon Inflammation-Disease Activity Index
- Energy Metabolism
- Heart Rate
- Hematocrit
- Hematological Parameters
- Hyperalgesia
- Indirect Calorimetry
- Relative Cerebral Blood Volume (rCBV)
- Respiration Rate
- Respirometry
- Serum Biochemistry
- Sleep Cycle Measurements
- Tiffeneau-Pinelli Index (FEV1/FVC Ratio)
- Vascular Conductance
Protein Structures
- Apolipoprotein E-Heparan Sulfate Proteoglycan (ApoE-HSPG) Complex
- Transthyretin-beta Amyloid (TTR-Aβ) Complex
Spectroscopy
- Atomic Absorption Spectrometry
- Bio-Layer Interferometry
- Capillary Gas Chromatography/Mass Spectrometry (GC/MS)
- Circular Dichroism
- Direct Analysis in Real Time (DART) Mass Spectrometry
- Electrospray Ionization Mass Spectrometry (ESI)
- Fourier Transform Infrared Microspectroscopy (FTIRM)
- Fourier Transform Infrared Spectroscopy (FTIR)
- High Resolution Magic Angle Spinning Spectroscopy (HRMAS)
- Inductively Coupled Plasma Mass Spectrometry (ICP-MS)
- Liquid Chromatography with Tandem Mass Spectrometry (LC/MS/MS)
- Liquid Chromatography-Mass Spectrometry (LC/MS)
- Magnetic Resonance Spectroscopy (MRS)
- Mass Cytometry
- Mass Spectrometry
- Matrix-Assisted Laser Desorption/Ionization-Time of Flight (MALDI-TOF) Mass Spectrometry
- Nuclear Magnetic Resonance Spectroscopy
- Pyrene Excimer Spectroscopy
- Saturation Transfer Difference Nuclear Magnetic Resonance (STD-NMR) Spectroscopy
- Spectrofluorometry
- Spectrophotometry
- Surface Plasmon Resonance (SPR) Spectroscopy
- Surface-Enhanced Laser Desorption/Ionization-Time Of Flight (SELDI-TOF) Mass Spectrometry
- Ultrahigh-Performance Liquid Chromatography with Quadruple Time Of Flight Mass Spectrometry (UHPLC-Q-TOFMS)
Toxicology
- Acute Adverse Drug Reactions
- Alanine Aminotransferase (ALT)
- Alkaline Phosphatase (ALP)
- Allergenic Properties
- Ames Test