Search Results

Displaying 1 - 15 of 917
APID Title Year PI Name Therapeutic Agent(s)
APID 42611218 Title A brain-penetrant triazolopyrimidine enhances microtubule-stability, reduces axonal dysfunction and decreases tau pathology in a mouse tauopathy model Year 2018 PI Name Brunden R Kurt Therapeutic Agent(s)
  • CNDR-51657
  • APID 32511005 Title The F(ab')2 fragment of an Aβ-specific monoclonal antibody reduces Aβ deposits in the brain Year 2005 PI Name Okuda Kenji Therapeutic Agent(s)
  • F2 fragment of anti Abeta Mab
  • APID 29860915 Title Effect of human umbilical cord blood derived lineage negative stem cells transplanted in amyloid-β induced cognitive impaired mice Year 2015 PI Name Anand Akshay Therapeutic Agent(s)
  • Human umbilical cord blood cells (HUCBC)
  • APID 28110917 Title Immunization of Tg-APPswe/PSEN1dE9 mice with Aβ3-10-KLH vaccine prevents synaptic deficits of Alzheimer’s disease Year 2017 PI Name Cao YunPeng Therapeutic Agent(s)
  • Aβ3-10-KLH
  • APID 27810817 Title A novel monoclonal antibody against the Nterminus of Aβ1-42 reduces plaques and improves cognition in a mouse model of Alzheimer's disease Year 2017 PI Name Chen Jian-Hong Therapeutic Agent(s)
  • 3F5 (anti Abeta Mab)
  • APID 26660817 Title Immunization with Bacillus Calmette-Guérin (BCG) alleviates neuroinflammation and cognitive deficits in APP/PS1 mice via the recruitment of inflammation-resolving monocytes to the brain Year 2017 PI Name Yao Bin Zhi Therapeutic Agent(s)
  • Bacillus Calmette-Guérin (BCG)
  • 4Aβ1-15
  • APID 26960817 Title Berberine improves cognitive impairment by promoting autophagic clearance and inhibiting production of β-amyloid in APP/tau/PS1 mouse model of Alzheimer's disease Year 2017 PI Name Guo Yi Therapeutic Agent(s)
  • Berberine
  • APID 25510816 Title Agrimonia pilosa Ledeb., Cinnamomum cassia Blume, and Lonicera japonica Thunb. protect against cognitive dysfunction and energy and glucose dysregulation by reducing neuroinflammation and hippocampal insulin resistance in β-amyloid-infused rats Year 2017 PI Name Park Sunmin Therapeutic Agent(s)
  • Lonicera japonica Thunb
  • Agrimonia pilosa Ledeb
  • Cinnamomum cassia Blume
  • APID 24060510 Title The therapeutic potential of human umbilical cord blood derived mesenchymal stem cells in Alzheimer’s disease Year 2010 PI Name Jin Hee Kyung Therapeutic Agent(s)
  • Human umbilical cord blood cells (HUCBC)
  • APID 24110615 Title 6-Phenoxy-2-phenylbenzoxazoles, novel inhibitors of receptor for advanced glycation end products (RAGE) Year 2015 PI Name Lee Jeewoo Therapeutic Agent(s)
  • 6-Phenoxy-2-phenylbenzoxazoles
  • APID 24910815 Title Erythropoietin improves synaptic plasticity and memory deficits by decrease of the neurotransmitter release probability in the rat model of Alzheimer's disease Year 2015 PI Name Haghani Masoud Therapeutic Agent(s)
  • Erythropoietin
  • APID 22810504 Title Aβ N-terminal-end specific antibody reduced b-amyloid in Alzheimer-model mice Year 2004 PI Name Yamaguchi Haruyasu Therapeutic Agent(s)
  • 82E1 (anti Abeta oligomer Mab)
  • APID 22160506 Title Active immunization trial in AB42-injected P301L tau transgenic mice Year 2006 PI Name Gotz Jurgen Therapeutic Agent(s)
  • beta amyloid peptide 1-42
  • APID 5860811 Title The second-generation active Aβ immunotherapy CAD106 reduces amyloid accumulation in APP transgenic mice while minimizing potential side effects Year 2011 PI Name Staufenbiel Matthias Therapeutic Agent(s)
  • CAD106
  • APID 5610809 Title Minocycline reduces the development of abnormal tau species in models of Alzheimer's disease Year 2009 PI Name Noble Wendy Therapeutic Agent(s)
  • Minocycline
  • Pages