Search Results

Displaying 1 - 15 of 1030
APID Title Year PI Name Therapeutic Agent(s)
APID 4510715 Title Beneficial effects of the beta-secretase inhibitor GRL-8234 in 5XFAD Alzheimer’s transgenic mice lessen during disease progression Year 2015 PI Name Ohno Masuo Therapeutic Agent(s)
  • GRL-8234
  • APID 4560715 Title Combined treatment with a BACE inhibitor and anti-abeta antibody gantenerumab enhances amyloid reduction in APP London mice Year 2014 PI Name Bohrmann Bernd Therapeutic Agent(s)
  • RO5508887
  • Gantenerumab
  • APID 4610714 Title Zileuton restores memory impairments and reverses amyloid and tau pathology in aged Alzheimer's disease mice Year 2014 PI Name Pratico Domenico Therapeutic Agent(s)
  • Zileuton
  • APID 4760713 Title Pioglitazone improves reversal learning and exerts mixed cerebrovascular effects in a mouse model of Alzheimer's disease with combined amyloid-β and cerebrovascular pathology Year 2013 PI Name Hamel Edith Therapeutic Agent(s)
  • Pioglitazone
  • APID 4810714 Title A neuroprotective brain-penetrating endopeptidase fusion protein ameliorates Alzheimer disease pathology and restores neurogenesis Year 2014 PI Name Spenser Brian Therapeutic Agent(s)
  • ASN12(neprilysin+brain target peptide)
  • APID 4860714 Title 7,8-dihydroxyflavone prevents synaptic loss and memory deficits in a mouse model of Alzheimer's disease Year 2014 PI Name Ye Keqiang Therapeutic Agent(s)
  • 7,8-dihydroxyflavone (7,8-DHF)
  • APID 4910714 Title Vaccine efficacy of transcutaneous immunization with amyloid β using a dissolving micro needle array in a mouse model of Alzheimer's disease Year 2014 PI Name Shinsaku Nakagawa Therapeutic Agent(s)
  • beta amyloid peptide 1-42
  • APID 5010713 Title The age-related gliosis and accompanying deficit in spatial learning are unaffected by dimebon Year 2013 PI Name Cowley R. Thelma Therapeutic Agent(s)
  • Dimebon
  • APID 5060710 Title Anti-inflammatory action of donepezil ameliorates tau pathology, synaptic loss, and neurodegeneration in a tauopathy mouse model Year 2010 PI Name Yoshiyama Yasumasa Therapeutic Agent(s)
  • Donepezil
  • APID 5110711 Title In-vivo histamine H3 receptor antagonism activates cellular signaling suggestive of symptomatic and disease modifying efficacy in Alzheimer’s disease Year 2011 PI Name Bitner R. Scott Therapeutic Agent(s)
  • ABT-239
  • Donepezil
  • APID 5160713 Title Tadalafil crosses the blood brain barrier and reverses cognitive dysfunction in a mouse model of AD Year 2013 PI Name García-Osta Ana Therapeutic Agent(s)
  • Tadalafil
  • Sildenafil
  • APID 5310713 Title Disease-modified glycogen synthase kinase-3beta intervention by melatonin arrests the pathology and memory deficits in an Alzheimer’s animal model Year 2013 PI Name Wang Jian-Zhi Therapeutic Agent(s)
  • Melatonin
  • APID 5360813 Title Phosphodiesterase 7 inhibitor reduced cognitive impairment and pathological hallmarks in a mouse model of Alzheimer’s disease Year 2013 PI Name Carro Eva Therapeutic Agent(s)
  • S14
  • APID 5410813 Title Selective benefits of simvastatin in bitransgenic APPSwe,Ind/TGF-b1 mice Year 2014 PI Name Hamel Edith Therapeutic Agent(s)
  • Simvastatin
  • APID 5460809 Title Oral apolipoprotein A-I mimetic peptide improves cognitive function and reduces amyloid burden in a mouse model of Alzheimer's disease Year 2009 PI Name Handattu Shaila Therapeutic Agent(s)
  • D-4F mimetic peptide
  • Pravastatin
  • Pages