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Displaying 1 - 15 of 1047
PubMed/DOI Title Year PI Name Therapeutic Agent(s)
PubMed/DOI 18360829 Title A nasal proteosome adjuvant activates microglia and prevents amyloid deposition Year 2008 PI Name Weiner L. Howard Therapeutic Agent(s)
  • Protollin
  • Glatiramer Acetate (GA)
  • PubMed/DOI 20017949 Title Acute dosing of latrepirdine (Dimebon), a possible Alzheimer therapeutic, elevates extracellular amyloid-beta levels in vitro and in vivo Year 2009 PI Name Gandy Sam Therapeutic Agent(s)
  • Dimebon
  • PubMed/DOI 18790460 Title Neuroprotection by hypothalamic peptide proline-rich peptide-1 in Aβ25–35 model of Alzheimer’s disease Year 2008 PI Name Sarkissian S. John Therapeutic Agent(s)
  • Proline-rich Peptide 1 (PRP-1)
  • PubMed/DOI 18590917 Title Melatonin prevents amyloid protofibrillar induced oxidative imbalance and biogenic amine catabolism Year 2008 PI Name Jayakumar Rajadas Therapeutic Agent(s)
  • Melatonin
  • PubMed/DOI 18677602 Title Prevention of pathological change and cognitive degeneration of Tg2576 mice by inoculating Aβ1-15 vaccine Year 2008 PI Name Yao ZhiBin Therapeutic Agent(s)
  • beta amyloid peptide 1-15
  • beta amyloid peptide 36-42
  • beta amyloid peptide 1-42
  • PubMed/DOI 18425343 Title Prevention of amyloid β-induced memory impairment by fluvastatin, associated with the decrease in amyloid β accumulation and oxidative stress in amyloid β injection mouse model Year 2008 PI Name Morishita Ryuichi Therapeutic Agent(s)
  • Fluvastatin
  • Simvastatin
  • PubMed/DOI 19940169 Title Adenosine A2A receptor blockade prevents synaptotoxicity and memory dysfunction caused by beta-amyloid peptides via p38 mitogen-activated protein kinase pathway Year 2009 PI Name Cunha A. Rodrigo Therapeutic Agent(s)
  • SCH58261
  • PubMed/DOI 18721865 Title Age-related expression of calcium/calmodulin-dependent protein kinase II A in the hippocampus and cerebral cortex of senescence accelerated mouse prone/8 mice is modulated by anti-Alzheimer's disease drugs Year 2009 PI Name Zhang Y.X- Therapeutic Agent(s)
  • Huperzine A
  • PubMed/DOI 19532137 Title Allele-specific RNAi mitigates phenotypic progression in a transgenic model of Alzheimer's disease Year 2009 PI Name Rodríguez-Lebrón Edgardo Therapeutic Agent(s)
  • rAAV-shAPPsw
  • PubMed/DOI 19146938 Title Ameliorative effects of yokukansan, a traditional Japanese medicine, on learning and non-cognitive disturbances in the Tg2576 mouse model of Alzheimer's disease Year 2009 PI Name Tabuchi Masahiro Therapeutic Agent(s)
  • Yokukansan
  • PubMed/DOI 15792351 Title The protective role of DL-α-lipoic acid in the oxidative vulnerability triggered by Aβ-amyloid vaccination in mice Year 2005 PI Name Jayakumar Rajadas Therapeutic Agent(s)
  • beta amyloid peptide 25-35
  • Alpha-Lipoic Acid (ALA)
  • PubMed/DOI 20971085 Title Anti-TNF-α reduces amyloid plaques and tau phosphorylation and induces CD11c-positive dendritic-like cell in the APP/PS1 transgenic mouse brains Year 2011 PI Name Xu Jun Therapeutic Agent(s)
  • Infliximab
  • PubMed/DOI 18585459 Title Protective effect of BDNF against beta-amyloid induced neurotoxicity in vitro and in vivo in rats Year 2008 PI Name Arancibia Sandor Therapeutic Agent(s)
  • Brain-derived neurotrophic factor (BDNF)
  • PubMed/DOI 19741145 Title Abeta immunotherapy: intracerebral sequestration of Abeta by an anti-Abeta monoclonal antibody 266 with high affinity to soluble Abeta Year 2009 PI Name Iwatsubo Takeshi Therapeutic Agent(s)
  • 10D5 (anti Abeta Mab)
  • 266 (anti Abeta Mab)
  • 82E1 (anti Abeta oligomer Mab)
  • PubMed/DOI 18555616 Title Minocycline provides protection against β-amyloid(25-35)-induced alterations of the somatostatin signaling pathway in the rat temporal cortex Year 2008 PI Name Arilla-Ferreiro Eduardo Therapeutic Agent(s)
  • Minocycline
  • Pages