Search Results

Displaying 1 - 15 of 740
APID Title Year PI Name Therapeutic Agent(s)
APID 46010613 Title Naringin Enhances CaMKII Activity and Improves Long-Term Memory in a Mouse Model of Alzheimer’s Disease Year 2013 PI Name Zhang Lian-Feng Therapeutic Agent(s)
  • Naringin
  • Donepezil
  • APID 46060613 Title A Novel Retro-Inverso Peptide Inhibitor Reduces Amyloid Deposition, Oxidation and Inflammation and Stimulates Neurogenesis in the APPswe/PS1DE9 Mouse Model of Alzheimer’s Disease. Year 2013 PI Name Allsop David Therapeutic Agent(s)
  • RI-OR2-TAT
  • APID 44760103 Title Anti-Amyloidogenic Effect of Allium sativum in Alzheimer's Transgenic Model Tg2576. Year 2003 PI Name Chauhan B Neelima Therapeutic Agent(s)
  • Allium sativum (Garlic)
  • APID 44810108 Title CD40L disruption enhances Aβ vaccine-mediated reduction of cerebral amyloidosis while minimizing cerebral amyloid angiopathy and inflammation. Year 2008 PI Name Tan Jun Therapeutic Agent(s)
  • beta amyloid peptide 1-42
  • CD40L antibody
  • APID 44860109 Title Grape seed polyphenols and curcumin reduce genomic instability events in a transgenic mouse model for Alzheimer’s disease. Year 2009 PI Name Fenech Michael Therapeutic Agent(s)
  • Grapeseed Extract
  • Curcumin
  • APID 44910109 Title First Demonstration of Cerebrospinal Fluid and Plasma Aβ Lowering with Oral Administration of a β-Site Amyloid Precursor Protein-Cleaving Enzyme 1 Inhibitor in Nonhuman Primates. Year 2009 PI Name Simon J Adam Therapeutic Agent(s)
  • Tertiary Carbinamine 1 (TC-1)
  • APID 44960109 Title Intramuscular delivery of a single chain antibody gene reduces brain Aβ burden in a mouse model of Alzheimer’s disease. Year 2009 PI Name Zhou Xin-Fu Therapeutic Agent(s)
  • rAAV2-scFv (anti-human beta amyloid single chain antibody)
  • APID 45010109 Title High Dietary Consumption of Trans Fatty Acids Decreases Brain Docosahexaenoic Acid but Does Not Alter Amyloid-β and Tau Pathologies in the 3xTg-AD Model of Alzheimer’s Disease. Year 2009 PI Name Calon Frederic Therapeutic Agent(s)
  • High-Fat Diet
  • APID 44261216 Title Selecting for neurogenic potential as an alternative for Alzheimer’s disease drug discovery. Year 2016 PI Name Schubert David Therapeutic Agent(s)
  • J147
  • CAD-31
  • Donepezil
  • APID 44311214 Title A coimmunization vaccine of Aβ42 ameliorates cognitive deficits without brain inflammation in an Alzheimer’s disease model. Year 2014 PI Name Wang Bin Therapeutic Agent(s)
  • Abeta 42 protein vaccine
  • pVAX1-Abeta 42 DNA vaccine
  • APID 44361214 Title Pharmacological characterization of the novel γ-secretase modulator AS2715348, a potential therapy for Alzheimer’s disease, in rodents and nonhuman primates. Year 2014 PI Name Mitani Yasuyuki Therapeutic Agent(s)
  • AS2715348
  • APID 44411214 Title Selenomethionine Ameliorates Cognitive Decline, Reduces Tau Hyperphosphorylation, and Reverses Synaptic Deficit in the Triple Transgenic Mouse Model of Alzheimer’s Disease. Year 2014 PI Name Liu Qiong Therapeutic Agent(s)
  • Selenomethionine
  • APID 44461214 Title Temsirolimus attenuates tauopathy in vitro and in vivo by targeting tau hyperphosphorylation and autophagic clearance. Year 2014 PI Name Tan Lan Therapeutic Agent(s)
  • Temsirolimus
  • APID 44510100 Title Reduction of Aβ accumulation in the Tg2576 animal model of Alzheimer's disease after oral administration of the phosphatidylinositol kinase inhibitor wortmannin. Year 2000 PI Name Eckman B Christopher Therapeutic Agent(s)
  • Wortmannin
  • APID 44560101 Title Antihistamine Agent Dimebon As a Novel Neuroprotector and a Cognition Enhancer. Year 2001 PI Name Sablin O Sergey Therapeutic Agent(s)
  • Dimebon
  • Pages