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Outcome Parameters List

Each Outcome Parameter falls within one or more Outcomes Measures. Choose the best Outcome Measure for a parameter from the drop down menu below, and view the Parameter options that fall within that Outcome Measure. If you do not see a Parameter that adequately describes your outcome, you may add your own terms within the SUBMIT YOUR DATA/OUTCOMES data entry form.
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Omics

  • Computational Drug Repositioning
  • Connectivity Map (CMap) Score
  • Cytokine Array Analysis
  • Drug-Exposure Gene Expression Profile
  • Expression Quantitative Trait Locus (eQTL) Analysis
  • Gene Expression Profile
  • Gene Expression Profile-Alzheimer's-Related Genes
  • Gene Expression Profile-Anti Oxidant Genes
  • Gene Expression Profile-Apoptotic Genes
  • Gene Expression Profile-Astrocytic Genes
  • Gene Expression Profile-Bioenergetics
  • Gene Expression Profile-Clock Genes
  • Gene Expression Profile-Dendritic Genes
  • Gene Expression Profile-Endothelial Markers
  • Gene Expression Profile-Immunity Genes
  • Gene Expression Profile-Inflammatory Genes
  • Gene Expression Profile-Microglial Genes
  • Gene Expression Profile-Phagocytic Markers
  • Gene Expression Profile-Protein Folding Genes
  • Gene Expression Profile-Sex Differences
  • Gene Expression Profile-Synaptic Genes
  • Gene Set Enrichment Analysis (GSEA)
  • Gut Microbiota
  • Lipidomics
  • Metabolomics
  • Micro Array Expression Analysis
  • Microbiota-Related Gene Set Enrichment Analysis (MSEA)
  • MicroRNA Expression Profile
  • MicroRNA-Gene Interaction Network
  • Protein Expression Profile
  • Protein Expression Profile-Alzheimer's-Related Proteins
  • Protein Expression Profile-Bioenergetics
  • Protein Expression Profile-Calcium Signaling Proteins
  • Protein Expression Profile-Immune Function
  • Protein Expression Profile-Mitochondrial Proteins
  • Protein Expression Profile-Sex Differences
  • Protein Set Enrichment Analysis (PSEA)
  • Protein-Protein Interaction (PPI) Map
  • Proteomics
  • Redox Proteomics
  • Significance Analysis of Microarrays (SAM)
  • Single-Cell RNA Sequencing
  • Whole Transcriptome Analysis

Pharmacodynamics

  • Acetylcholine Release
  • Target Engagement (Activation 5-hydroxytryptamine 6 Receptor)
  • Target Engagement (Activation AMP-Activated Protein Kinase)
  • Target Engagement (Activation cAMP Response Element-Binding Protein)
  • Target Engagement (Activation Cannabinoid Receptor 2)
  • Target Engagement (Activation GABA-A Receptor)
  • Target Engagement (Activation Nicotinic Cholinergic Receptor)
  • Target Engagement (Activation p75 Neurotrophin Receptor)
  • Target Engagement (Activation Peroxisome Proliferator-Activated Receptor gamma)
  • Target Engagement (Activation Protein Kinase C alpha)
  • Target Engagement (Activation Tyrosine Receptor Kinase B)
  • Target Engagement (Activation Vitamin D Receptor)
  • Target Engagement (Binding Antibody to Amyloid Precursor Protein)
  • Target Engagement (Binding Antibody-Sera to beta Amyloid Deposits)
  • Target Engagement (Binding beta Amyloid Antibodies to beta Amyloid Deposits)
  • Target Engagement (Binding mGluR5 Receptor)
  • Target Engagement (Binding Nanoparticles to beta Amyloid Deposition)
  • Target Engagement (Binding NMDA Receptor)
  • Target Engagement (Binding to Corticotropin-Releasing Factor Receptors)
  • Target Engagement (Binding to Nicotinic Cholinergic Receptor alpha 7 Subunit)
  • Target Engagement (Binding to Tau Protein)
  • Target Engagement (C9 Inhibition of Proinflammatory Molecules is Blocked by CMKLR1 Antagonist)
  • Target Engagement (Clearance beta Amyloid Deposits)
  • Target Engagement (Complex of Antibody with Amyloid-Brain)
  • Target Engagement (Complex of Antibody with beta Amyloid-CSF/Plasma)
  • Target Engagement (Displacement of beta Amyloid Oligomers)
  • Target Engagement (Increased Angiotensin I Converting Enzyme 2 Activity)
  • Target Engagement (Increased Apolipoprotein E Level)
  • Target Engagement (Increased ATP Binding Cassette Subfamily A Member 1 Level)
  • Target Engagement (Increased beta Amyloid Peptide 38-Brain)
  • Target Engagement (Increased beta Amyloid Peptide 38-CSF)
  • Target Engagement (Increased beta Catenin)
  • Target Engagement (Increased Cathepsin B Activity)
  • Target Engagement (Increased Cathepsin B Level)
  • Target Engagement (Increased CD3+ T Cells-Brain)
  • Target Engagement (Increased Glucose Uptake)
  • Target Engagement (Increased Insulin Sensitivity-Blood)
  • Target Engagement (Increased Interferon gamma)
  • Target Engagement (Increased Liver X Receptor)
  • Target Engagement (Increased Microglial Phagocytosis)
  • Target Engagement (Increased Microglial Proliferation)
  • Target Engagement (Increased O-GlcNAcase Level)
  • Target Engagement (Increased O-GlcNAcylated Protein Level)
  • Target Engagement (Increased Soluble Amyloid Precursor Protein alpha)
  • Target Engagement (Increased Synaptic ADAM10)
  • Target Engagement (Increased Tyrosine Phosphorylation)
  • Target Engagement (Inhibition 12/15-Lipoxygenase)
  • Target Engagement (Inhibition 5-hydroxytryptamine 7 Receptor)
  • Target Engagement (Inhibition 5-Lipoxygenase)
  • Target Engagement (Inhibition Acetylcholinesterase)
  • Target Engagement (Inhibition Angiotensin Converting Enzyme )
  • Target Engagement (Inhibition Butyrylcholinesterase)
  • Target Engagement (Inhibition c-Jun N-terminal Kinase)
  • Target Engagement (Inhibition Cathepsin B)
  • Target Engagement (Inhibition CD33 Gene Expression)
  • Target Engagement (Inhibition Cyclooxygenase 1/2)
  • Target Engagement (Inhibition Farnesytransferase)