Literature Supporting Reproducibility

Literature Supporting Reproducibility

Guidelines to improve animal study design and reproducibility for Alzheimer's disease and related dementias: For funders and researchers. (Snyder et al., Alzheimer's & Dementia, 2016; Nov;12(11):1177-1185)
Accelerating drug discovery for Alzheimer's disease: Best practices for preclinical animal studies. (Shineman et al., Alzheimer's Research & Therapy, 2011;3(5):28)
Preclinical models of Alzheimer's disease: Relevance and translational validity. (Mullane et al., Current Protocols in Pharmacology, 2019; 84, e57:1-28)
Practical considerations for choosing a mouse model of Alzheimer's disease. (Jankowsky et al., Molecular Neurodegeneration, 2018; Dec 22;12(1):89)
Harnessing genetic complexity to enhance translatability of Alzheimer's disease mouse models: A path toward precision medicine. (Neuner et al., Neuron, 2019 Feb 6;101(3):399-411)
Improving bioscience research reporting: the ARRIVE guidelines for reporting animal research. (Kilkenny et al., Osteoarthritis Cartilage, 2012;20(4):256-60)
The ARRIVE guidelines 2.0: Updated guidelines for reporting animal research. (Percie du Sert et al., PLOS Biology, 2020; 18(7):e3000410)
The Experimental Design Assistant. (Percie du Sert et al., Nature Methods, 2017; 14:1024–1025)
The need for randomization in animal trials: an overview of systematic reviews. (Hirst, J.A., et al., PLoS One, 2014; 9(6): p. e98856)
Framework for advancing rigorous research. (Koroshetz et al., eLife, 2020; 9: e55915)

Two decades testing interventions in transgenic mouse models of Alzheimer's disease: designing and interpreting studies for clinical trial success. (Egan et al., Clinical Investigation London, 2014;4(8):693-704)

Did a change in Nature journals’ editorial policy for life sciences research improve reporting? (The NPQIP Collaborative Group, BMJ Open Science, 2019; 3(1): p. e000035)

The MDAR (Materials Design Analysis Reporting) Framework for transparent reporting in the life sciences. (Mcleod et al., PNAS, 2021; Vol. 118 No. 17 e2103238118)

Conserved cell types with divergent features in human versus mouse cortex. (Hodge et al., Nature, 2019; 573(7772):61-68)
Sex as a biological variable: A 5-year call to action. (Arnegard et al., J Womens Health; 2020 Jun;29(6):858-864)
Are hormones a "female problem" for animal research? (Shansky, Science, 2019; 364(6443): 825-826)

Policy: NIH plans to enhance reproducibility. (Collins et al., Nature, 2014;505(7485):612-3)
Policy: NIH to balance sex in cell and animal studies. (Clayton & Collins, Nature, 2014; 509, pages: 282–283)

Applying the new SABV (sex as a biological variable) policy to research and clinical care. (Clayton, Physiology & Behavior, 2018; 187:2-5)
Studying both sexes: A guiding principle for biomedicine. (Clayton, FASEB J. 2016; 30, 519-524)

Reporting and misreporting of sex differences in the biological sciences. (Garcia-Sifuentes et al., eLife, 2021;0:e70817)

Sex difference analyses under scrutiny. (Vorland, eLife, 2021;10:e74135)

Analysis of sex and gender reporting policies in preeminent biomedical journals. (Bibb et al., JAMA Network Open, 2022;5(8):e2230277)

A framework for sex, gender, and diversity analysis in research. (Hunt et al., Science, 2022; Vol 377 Issue 6614)

Is it possible to overcome issues of external validity in preclinical animal research? Why most animal models are bound to fail. (Pound et al., Journal of Translational Medicine, 2018; Nov 7;16(1):304)

Preclinical research: Make mouse studies work. (Perrin, Nature, 2014;507(7493):423-5)

A call for transparent reporting to optimize the predictive value of preclinical research. (Landis et al., Nature, 2012;490(7419):187-91)

Promoting an open research culture. (Nosek et al., Science, 2015; 348(6242):1422-5)

The value and limitations of transgenic mouse models used in drug discovery for Alzheimer's disease: An update. (Bales, Expert Opinion on Drug Discovery, 2012;7(4):281-97)

Can animal models of disease reliably inform human studies? (van der Worp et al., PLoS Medicine, 2010;7(3):e1000245)

Publication bias in reports of animal stroke studies leads to major overstatement of efficacy. (Sena et al., PLoS Biology, 2010;8(3):e1000344)

'Too much good news' - are Alzheimer mouse models trying to tell us how to prevent, not cure, Alzheimer's disease? (Zahs et al., Trends in Neurosciences, 2010;33(8):381-9)

The rat as an animal model of Alzheimer's disease. (Benedikz et al., Journal of Cellular and Molecular Medicine, 2009;13(6):1034-42)

Removing obstacles in neuroscience drug discovery: The future path for animal models. (Markou et al., Neuropsychopharmacology, 2009;34(1):74-89)

Design, power, and interpretation of studies in the standard murine model of ALS. (Scott et al., Amyotrophic Lateral Sclerosis, 2008;9(1):4-15)

Accelerating biomedical discoveries through rigor and transparency. (Hewitt et al., ILAR Journal, 2017, Vol. 58, No. 1, 115–128)

The costs of reproducibility. (Poldrak, Neuron, 2019; Jan 2;101(1):11-14)

Journals unite for reproducibility. (Editorial, Nature, 2014; 515:7)
Fixing problems with cell lines. (Lorsch et al., Science 2014; Vol 346, Issue 6216; pp. 1452-1453)

Rigor or mortis: Best practices for preclinical research in neuroscience. (Steward et al., Neuron, 2014; 84(3):572-81)

Improving and Accelerating Therapeutic Development for Nervous System Disorders: Workshop Summary. Washington DC: 2014 by the National Academy of Sciences; 2014.

Improving the Utility and Translation of Animal Models for Nervous System Disorders: Workshop Summary. Washington DC: National Academy of Sciences.; 2013.

Scientists routinely cure brain disorders in mice but not us. A new study helps explain why. (Begley, STAT+ 2019)

Do the 3Rs need to evolve for modern translational research with mice? (Keater, Ampersand/The Primer Blog, 2022)

Additional literature on rigor and reproducibility in preclinical research

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