Search Results

Displaying 1 - 6 of 6
APID Title Yearsort ascending PI Name Therapeutic Agent(s)
APID 56810919 Title Enhancement of tripartite synapses as a potential therapeutic strategy for Alzheimer’s disease: a preclinical study in rTg4510 mice Year 2019 PI Name Lin G. Chien-Liang Therapeutic Agent(s)
  • LDN/OSU-0215111
  • APID 46360619 Title A farnesyltransferase inhibitor activates lysosomes and reduces tau pathology in mice with tauopathy Year 2019 PI Name Kosik S. Kenneth Therapeutic Agent(s)
  • Lonafarnib
  • Rhes-targeted microRNA (Rhes-miR)
  • APID 30720917 Title Inhibition of O-GlcNAcase leads to elevation of O-GlcNAc tau and reduction of tauopathy and cerebrospinal fluid tau in rTg4510 mice Year 2017 PI Name Duffy L. Joseph Therapeutic Agent(s)
  • Thiamet G
  • APID 33011017 Title Passive immunization with phospho-tau antibodies reduces tau pathology and functional deficits in two distinct mouse tauopathy models Year 2015 PI Name Sankaranarayanan Sethu Therapeutic Agent(s)
  • PHF13 (anti-pS396 tau MAb)
  • PHF6 (anti-pT231 tau MAb)
  • APID 21311214 Title Methylene blue does not reverse existing neurofibrillary tangle pathology in the rTg4510 mouse model of tauopathy Year 2014 PI Name Spires-Jones L. Tara Therapeutic Agent(s)
  • Methylthioninium Chloride (MTC)
  • APID 32911014 Title Increased O-GlcNAcylation reduces pathological tau without affecting its normal phosphorylation in a mouse model of tauopathy Year 2014 PI Name Hering Heike Therapeutic Agent(s)
  • Thiamet G